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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
40
Human Site:
S1352
Identified Species:
73.33
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
S1352
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
S1352
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
S1352
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Dog
Lupus familis
XP_851777
2404
260682
S1353
D
S
G
E
M
S
E
S
F
P
Y
R
T
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S1389
D
S
G
E
M
S
E
S
F
P
Y
R
T
K
A
Rat
Rattus norvegicus
XP_001076610
2413
263563
S1350
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
S1366
D
S
G
E
M
A
E
S
F
P
Y
R
T
K
A
Frog
Xenopus laevis
NP_001088637
2428
264402
S1379
D
T
G
E
M
P
E
S
F
P
Y
R
T
K
A
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
S1361
D
S
G
E
M
S
E
S
F
P
Y
K
S
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
E2009
E
Q
G
E
M
M
N
E
F
P
Y
R
A
K
A
Honey Bee
Apis mellifera
XP_001122031
2606
284119
E1588
E
N
G
D
M
P
G
E
F
P
Y
R
A
K
A
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
Y1170
K
A
Q
M
K
Q
K
Y
V
E
S
N
Q
F
P
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
T1596
Y
G
D
D
L
P
D
T
F
P
Y
R
S
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
N.A.
100
86.6
80
N.A.
60
53.3
0
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
66.6
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
39
0
0
0
0
0
0
16
0
93
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
8
16
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
77
0
0
70
16
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
8
0
% F
% Gly:
0
8
85
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
8
0
0
0
0
8
0
93
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
85
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
24
0
0
0
93
0
0
0
0
8
% P
% Gln:
0
8
8
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% R
% Ser:
0
62
0
0
0
24
0
70
0
0
8
0
16
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
0
0
62
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
93
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _